As the use of neoadjuvant chemotherapy is gradually increased in the treatment of breast cancer, evaluating its therapeutic effect is gaining importance. This study investigated the correlation between pharmacokinetic parameters using high spatial and temporal resolution dynamic contrast-enhanced MR imaging (DCE-MRI) and the prognostic factors for breast cancers. The results showed quantitative parameters (Ktrans, kep) were significantly correlated to the prognostic factors (PR, Ki-67) of breast cancers. Quantitative parameters (Ktrans, kep) of high spatial and temporal resolution DCE-MRI may be good indicators of therapeutic effect of patients undergoing neoadjuvant treatment.
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