Abstract #4906

Ultra-fast balanced SSFP signal enhancement ratio mapping of the human lung parenchyma at 1.5T

Orso Pusterla^1,2, Gregor Sommer³, Mark Wiese⁴, Didier Lardinois⁴, Michael Tamm⁵, Jens Bremerich³, Francesco Santini^1,2, Grzegorz Bauman^1,2, and Oliver Bieri^1,2

¹Department of Radiology, Division of Radiological Physics, University of Basel Hospital, Basel, Switzerland, ²Department of Biomedical Engineering, University of Basel, Basel, Switzerland, ³Clinic of Radiology and Nuclear Medicine, Cardiac and Thoracic Imaging, University of Basel Hospital, Basel, Switzerland, ⁴Clinic of Thoracic Surgery, University of Basel Hospital, Basel, Switzerland, ⁵Clinic of Pneumology, University of Basel Hospital, Basel, Switzerland

In this work, we propose a new conceptual framework for functional pulmonary parenchyma imaging in the clinical setup from two volumetric ultra-fast balanced steady-state free precession (ufSSFP) breath-hold acquisitions before and after contrast agent administration. The resulting signal enhancement ratio (SER) maps of the parenchyma in patients shows similarity to SPECT/CT fusion images. The method requiring only two breath-hold acquisitions is rapid and amenable for clinical use.

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