Abstract #4905

4D and 2D phase-contrast MRI for the evaluation of pulmonary artery hemodynamics in patients with pulmonary hypertension and healthy volunteers

Malte Sieren¹, Clara Berlin¹, Thekla Helene Oechtering¹, Peter Hunold¹, Daniel Droemann², Joerg Barkhausen¹, and Alex Frydrychowicz¹

¹Clinic for Radiology and Nuclear Medicine, University Hospital Schleswig-Holstein, Lübeck, Germany, ²Medical Clinic III, Pulmonology, University Hospital Schleswig-Holstein, Lübeck, Germany

2D and 4D phase-contrast MRI (PC MRI) has been subject of recent studies to noninvasively diagnose pulmonary hypertension. The aim of this study was to compare values derived from both imaging techniques in a study collective consisting of healthy volunteers and patients with PH. Although 4D PC MRI generates higher quantitative values in comparison to 2D PC MRI, both sequences were able to distinguish volunteers from patients. In addition, 4D PC MRI visualized blood flow, underlining its additional value to detect secondary flow patterns in patients.

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