Although outcome of acute cardiogenic cerebral embolism patients improved dramatically due to development of interventional devices, sub-acute cases over the golden period still follow miserable clinical courses requiring to elucidate the pathology of cerebral ischemia. The authors attempted to unveil the correlation of clinical features following cardiogenic cerebral embolism and the locations or sizes of the infarction using voxel-based lesion mapping (VBLM). Our result revealed a correlation between spatial characteristics of infarction and clinical features. Larger ischemic volume at the left hemisphere is correlated with patient’s outcome and cerebral herniation was strongly influenced by ischemic volume after standardization.
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