Microstructural brain changes before, 1-month and 6-months and after working Memory Training was evaluated in both HIV-positive and seronegative individuals. While working memory training improved performance in both trained and non-trained working memory tasks, brain diffusivities increased in most brain regions after training in both groups, more in HIV than controls in some regions. These findings suggest ongoing brain inflammation associated with normal aging or HIV may mask the training-related changes in DTI measures.
This abstract and the presentation materials are available to members only; a login is required.