With chemical-exchange sensitive imaging, increasing field narrows the linewidth of magnetization transfer effects and shifts relative exchange rates (exchange rate vs. chemical shift) toward a slower exchange regime. This study is intended to explore the interplay of contrast mechanisms and sensitivity benefits by comparing phantom and in-vivo data acquired at the fields of 9.4T and 15.2T. The linewidth narrowing effect between the fields is demonstrated in agar phantoms with nicotinamide as well as spectra from the rat cortex. Spectra taken at higher power shows increase of sensitivity by shifting toward a slower exchange regime.
This abstract and the presentation materials are available to members only; a login is required.