Abstract #3429

Determination of Droplet Size Distribution in Brown Adipose Tissues by Diffusion NMR Spectroscopy

Sanjay Kumar Verma¹, Jadegoud Yaligar¹, Navin Michael², Tian Xianfeng¹, Venkatesh Gopalan¹, Suresh Anand Sadananthan², Rengaraj Ananthraj¹, and S. Sendhil Velan^1,2

¹Laboratory of Molecular Imaging, Singapore Bioimaging Consortium, Singapore, Singapore, ²Singapore Institute for Clinical Sciences, Singapore

Non-Invasive Imaging of Brown Adipose Tissue is of significant interest due to its potential to combat obesity and diabetes. In this study, we have utilized diffusion spectroscopy to estimate the droplet size distribution in chow and high-fat diet fed brown adipose tissues obtained from rodents. The high-fat diet BAT exhibited reduction in the restriction due to the increase in droplet size. The histology results confirm the droplet size distribution in both control and high-fat diet tissues.

This abstract and the presentation materials are available to members only; a login is required.

Join Here