Studied longitudinally 21 PD patients using Eigenvector centrality mapping,discovered significantly decreased EC values in right postcentral gyrus, and increased EC values in right cerebellum, right supplementary motor area (right SMA) as compared to B group. right postcentral gyrus in F group is negativelycorrelatedwithhoehn and yahr staging( HY) stage (r =-0.48, p < 0.05). Variation of EC values (F group-B group) in right cerebellum is positively correlated with changeofUPDRS-III scores. The current study demonstrated that deterioration and compensation exists through different circuit along with PD progression.
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