Abstract #1942

An optimised 2D MPRAGE sequence for T1 contrast in the fetal brain: application to slice to volume reconstruction and multiband acceleration

Giulio Ferrazzi¹, Anthony N. Price¹, Rui Pedro AG Teixeira¹, Francesco Padormo², Lucilio Cordero-Grande¹, Emer Hughes¹, Laura McCabe¹, Mary Rutherford¹, Maria Kuklisova Murgasova¹, and Joseph V. Hajnal¹

¹Division of Imaging Sciences & Biomedical Engineering, King's College London, London, United Kingdom, ²Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, United States

Ultrafast single-shot T₂ weighted images are common practise in fetal MR exams. However, there is limited experience with fetal T₁ acquisitions.

In this study, a 2D gradient echo sequence with an adiabatic inversion was optimized to be robust to fetal motion and to preserve contrast. We also explore slice to volume registration and super resolution reconstruction methods to enhance the resolution, and we show pilot data from a multiband accelerated version of the above-mentioned sequence.

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