Abstract #1938

Relaxation Times and Magnetic Susceptibility of Human Umbilical Cord Blood at 3 Tesla

Sharon Portnoy¹, Natasha Milligan², Mike Seed^3,4, John G. Sled^1,5, and Christopher K. Macgowan^1,6

¹Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada, ²Department of Obstetrics and Gynecology, Mount Sinai Hospital, Toronto, ON, Canada, ³Department of Pediatrics and Diagnostic Imaging, University of Toronto, Toronto, ON, Canada, ⁴Division of Cardiology, The Hospital for Sick Children, Toronto, ON, Canada, ⁵Mouse Imaging Centre, The Hospital for Sick Children, Toronto, ON, Canada, ⁶Department of Physiology and Experimental Medicine, The Hospital for Sick Children, Toronto, ON, Canada

With an increasing proportion of fetal cardiovascular MRI scans being performed at 3 Tesla, there is growing need for an accurate calibration, which characterizes relationships between MRI properties (T₁, T₂, susceptibility) and blood properties (oxygen-saturation, sO₂ and hematocrit, Hct) at 3T. Accordingly, relaxometry measurements were performed at 3T on cord blood specimens (N=89) with a broad range of hematocrits (0.09<Hct<0.82) and oxygen-saturations (7%<sO₂<100%). We also measured fetal blood susceptibility, which, to our knowledge, has never been reported. The data were effectively described by a simple, two-compartment model for blood.

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