We propose a new approach to IVIM analysis using computed DWI (cDWI) based on stretched exponential model. IVIM analysis is widely studied clinically to evaluate tissue perfusion and diffusivity using a range of low and high b values. However, signal attenuation curves of different b values are heterogeneous because of biological effects from multiple components and patient’s motion during the acquisition. So we generated cDWI first using stretched exponential model which can better fit for signal attenuation curve and analyse IVIM parametric maps using cDWI. The proposed approach can fit more robustly the IVIM model parameters.
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