Abstract #1100

3T 1H PRESS (TE 68 ms) reveals elevated cerebral glucose in patients with diabetes mellitus type 2, which is associated with fasting blood glucose

Frank C.G. van Bussel¹, Tamar M van Veenendaal¹, Miranda T Schram², Coen D.A. Stehouwer², Walter H Backes¹, and Jacobus F.A. Jansen¹

¹Radiology, Maastricht University Medical Center, Maastricht, Netherlands, ²Internal Medicine, Maastricht University Medical Center, Maastricht, Netherlands

A standard 1H PRESS sequence, with a TE of 68 ms, acquired at 3T is applied to investigate differences in cerebral glucose concentrations in type 2 diabetes mellitus (T2DM ) compared with controls with normal glucose metabolism. Subjects with T2DM (n=38) display an increased cerebral glucose level compared to controls (n=38). These levels are also associated with two blood glucose measures, fasting blood glucose (FBG) and glycated hemoglobin (HbA1c).

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