Abstract #0982

3D printed Breast DCE-MRI phantom to mimic structure and pharmacokinetics

Nithin N Vajuvalli¹, Chethan Kumar M¹, Amaresha Shridhar Konar^1,2, Shivaprasad Ashok Chikop¹, Darshan Shivaramu Keelara¹, Ashwini Kumnoor¹, Ramesh Venkatesan², and Sairam Geethanath¹

¹Medical Imaging Research Centre, Dayananda Sagar Institution, Bangalore, India, ²Wipro GE healthcare, Bangalore, India

DCE MRI plays a critical role in routine clinical breast examination. Current work focuses on the development of Breast DCE MRI phantom using a 3D printer to mimic poor and well perfused regions. The phantom developed was controlled through user entered K^trans values entered in a GUI which interfaced with a peristaltic pump to control flow rates. The K_ep parameters was controlled through the 3D model geometry. Prospective MR images of the phantom were acquired on a 1.5T scanner using the TRICKS sequence; and pharmacokinetic maps based on Tofts model were computed and quantified.

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