The temporal scaling of the diffusion coefficient and diffusional kurtosis may reveal the underlying microstructural features of the human brain. Here we demonstrate time-dependent diffusion coefficient and kurtosis in gray matter areas of the human brain in vivo. Our results suggest that the major contribution of time-dependence in gray matter originates from intra-neurite water with the main source of restrictions, e.g. dentrites and beads, being short-range disordered in their placement.
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