Abstract #0366

A paradoxical systemic bias in Gd-EOB-DTPA-enhanced T1 relaxometry of the liver: a comparison of SMART1Map and MOLLI.

Akira Yamada¹, Sachie Fujita¹, Yoshihiro Kitoh², Yasuo Adachi², Hayato Hayashibara², Aya Shiobara², Atsushi Nozaki³, Yuji Iwadate³, Glenn S Slavin⁴, Yasunari Fujinaga¹, and Masumi Kadoya¹

¹Department of Radiology, Shinshu Univ. School of Medicine, Matsumoto, Japan, ²Department of Radiology, Shinshu Univ. Hospital, Matsumoto, Japan, ³GE Healthcare Japan, Japan, ⁴GE Healthcare, United States

SMART₁Map (saturation method using adaptive recovery times for cardiac T1 mapping) is a new single-point T1 mapping technique that directly measures true T1 unlike look-locker approaches. The feasibility of Gd-EOB-DTPA-enhanced T1 relaxometry of the liver using SMART1Map was evaluated comparing with modified look-locker inversion recovery (MOLLI). A significant paradoxical systemic bias was observed between and within SMART₁Map and MOLLI in Gd-EOB-DTPA-administrated liver, although SMART₁Map may be more reproducible than MOLLI in the rest of conditions. Careful consideration should be given to the effect of the paradoxical systemic bias in the evaluation of liver function using Gd-EOB-DTPA-enhanced T1 relaxometry.

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