Diffusion magnetic resonance imaging is still the unique tool capable of probe the structure of the brain connectivity in vivo. Although some great advances have been made in the past decade, reconstructed tractograms often lack of anatomically accuracy. The introduction of anatomical priors has become a promise land to tackle this issue, so in this work, we propose a general spin-glass-based global tractography framework constrained by anatomical priors to better represent the sharp turns of fibers entering a gyrus and connecting to the pial surface.
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