Abstract #4405
Reduction of hippocampal blood flow in collegiate football players
Michael Zeineh 1 , David Douglas 1 , Mansi Parekh 1 , Eugene Wilson 1 , Sherveen Parivash 2 , Lex Mitchell 3 , Brian Boldt 1 , Wei Scott Bian 1 , Scott Anderson 4 , Andrew Hoffman 5 , Huy Scott Do 1 , Gerald Scott Grant 6 , Jamshid Scott Ghajar 6 , and Greg Zaharchuk 1
1
Radiology, Stanford University, Stanford,
California, United States,
2
Duke
University, North Carolina, United States,
3
Evans
Army Community Hospital, Fort Carson, Colorado, United
States,
4
Sports
Medicine, Stanford University, Stanford, California,
United States,
5
Internal
Medine, Stanford University, Stanford, California,
United States,
6
Neurosurgery,
Stanford University, Stanford, California, United States
Head injury is common in contact sports and can have
long-term consequences. Brain perfusion may be reduced
to regions of injury and can be measured noninvasively
with MRI. We performed arterial spin labeling (ASL) on
47 football players, comparing with 21 control
volleyball players. This demonstrated reduced perfusion
in the hippocampi and thalami. The effect size of the
reduced perfusion was much greater than for traditional
volumetric analysis of the hippocampi. ASL may be a
useful metric for evaluating mild traumatic brain injury
in sports.
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