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Abstract #4181

Comparison of T1rho imaging between spoiled gradient echo (SPGR) and balanced steady state free precession (b-FFE) sequence of knee cartilage at 3 tesla

Taiki Nozaki 1 , Yasuhito Kaneko 1 , Hon J. Yu 1 , Kayleigh Kaneshiro 1 , Ran Schwarzkopf 2 , and Hiroshi Yoshioka 1

1 Radiological Sciences, University of California, Irvine, Orange, California, United States, 2 Orthopaedic Surgery, University of California, Irvine, Orange, California, United States

T1rho-weighted MR imaging has recently been proposed as an attractive biomarker to existing conventional morphological MRI methods, and enables us to detect early cartilage degeneration in early osteoarthritis patients before appearing morphological change. However the factors affecting the T1rho mapping such as MR sequences and operator-dependent manual cartilage segmentation is not well understood. The objective of this study was to investigate the difference of T1rho profiles between spoiled gradient echo (SPGR) and balanced steady state free precession (b-FFE) sequences.

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