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Abstract #4180

Optimization of adiabatic T 1 and T 2 for quantification of articular cartilage at 3T

Victor Casula 1,2 , Mikko J. Nissi 3,4 , Joonas Autio 3 , Michaeli Shalom 4 , Silvia Mangia 4 , Edward Auerbach 4 , Jutta Ellermann 4 , Eveliina Lammentausta 3 , and Miika T. Nieminen 1,3

1 Radiology, University of Oulu, Oulu, Oulu, Finland, 2 Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Oulu, Finland, 3 Department of Diagnostic Radiology, Oulu University Hospital, Oulu, Finland, 4 Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, United States

Adiabatic T 1 lower case Greek rho and T 2 lower case Greek rho sequences were evaluated with a 3 T clinical system. The optimal parameters for in vivo quantitative imaging of articular cartilage were determined on the basis of the evaluation of relaxation time maps and in order to minimize scanning time and power deposition and maximize image quality. The results show that adiabatic T 1 lower case Greek rho and adiabatic T 1 lower case Greek rho are suitable for in vivo quantitative assessment of articular cartilage at 3 T. The preliminary results are encouraging when the techniques were applied to discriminate normal and early osteoarthritis cartilage.

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