Abstract #4001
Evaluation of b-value distributions for monoexponential model of prostate cancer diffusion-weighted imaging using b values up to 2000 s/mm 2 : a repeatability study on region of interest level
Harri Merisaari 1 , Jussi Toivonen 2 , Marko Pesola 3 , Pekka Taimen 4 , Peter J Bostrm 5 , Tapio Pahikkala 2 , Hannu J Aronen 3 , and Ivan Jambor 3
1
Turku PET Centre, University of Turku,
Turku, Finland,
2
Department
of Information Technology, University of Turku, Turku,
Finland,
3
Department
of Diagnostic Radiology, University of Turku, Turku,
Finland,
4
Department
of Pathology, Turku University Hospital, Turku, Finland,
5
Department
of Urology, Turku University Hospital, Turku, Finland
We elevated the effect of 4083 different b-value
combinations on the prostate cancer detection, Gleason
score prediction, and repeatability of monoexponential
model for diffusion weighted imaging (DWI) using
b-values up to 2000 s/mm
2
. Fifty patients
with histologically confirmed PCa underwent two repeated
3T MRI examinations before radical prostatectomy. DWI
was performed using 12 equally distributed b-values.
B-value distributions containing only b values in end of
the b-value range (~1500 to 2000 s/mm
2
)
demonstrated the lowest diagnostic performance and
repeatability while the rest of b values distributions
had similar performance and repeatability.
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