Abstract #3952
Observing the activity change of the baseline brain in Benign Essential Blepharospasm with fractional amplitude of low-frequency fluctuation
Mingfei Ni 1 , Weiwei Wang 1 , Ziheng Zhang 2 , Qingwei Song 1 , Ailian Liu 1 , and Yanwei Miao 1
1
Radiology Department, the First Affiliated
Hospital of Dalian Medical University, Dalian, Liaoning,
China,
2
GE
Healthcare China, Beijing, China
Objective:To investigate the activity changes of the
baseline brain in patients with Benign Essential
Blepharospasm (BEB) by resting-state fMRI fractional
amplitude of low-frequency fluctuation (fALFF)
method.Methods:28 patients with BEB and 28 healthy
controls group were scanned on a 3.0T MRIscanner. The
image data were analyzed with software SPM8, DPARSF and
REST. Results The whole brain analysis indicated that in
comparison with the normal control group, there was a
ncreased fALFF in the right major sensorimotor
arearight caudate headleft thalamus. the fALFF in
the left thalamus were positively correlated with the
JRS total score.
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