Abstract #3592
MRI Characterizations of Region Specific White Matter Hyperintensities and Vertebral Artery Stenosis
Liya Wang 1,2 , Adrian Lam 3 , John Oshinski 2 , Xiaodong Zhong 4 , Chad A Holder 2 , Felicia Goldstein 5 , Diana Ge 2 , and Hui Mao 1,2
1
Laboratory of Functional-Molecular Imaging
and Nanomedicine, Emory University School of Medicine,
Atlanta, Georgia, United States,
2
Radiology
and Imaging Sciences, Emory University School of
Medicine, Atlanta, Georgia, United States,
3
Biomedical
Engineering, Georgia Institute of Technology, Atlanta,
Georgia, United States,
4
MR
R&D Collaborations, Siemens Healthcare, Atlanta,
Georgia, United States,
5
Neurology,
Emory University School of Medicine, Atlanta, Georgia,
United States
Cerebrovascular diseases may cause cognitive functions
decline. Comprehensive MRI approaches used to
characterize white matter hyperintensity (WMH), cerebral
blood flow (CBF), and vertebral artery (VA) stenosis in
patients with cerebral vascular and cardiovascular
risks. It demonstrated that VA stenosis characterized as
vascular narrowing and/or reduced CBF by MRI may be
associated with the regional specific cerebral vascular
comorbidities detected as WMH and reduction of CBF. The
comprehensive MRI protocols with functional and high
resolution structural imaging sequences are capable of
providing valuable information on blood flow supply in
the VA and cerebrovascular ischemia in individuals
having vertebral and cardiovascular abnormalities.
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