Abstract #3591
Exercise Intensity Modulates the Change in Cerebral Blood Flow Following Aerobic Exercise in Chronic Stroke: a PCASL Study
Andrew D. Robertson 1 , David E. Crane 1 , A. Saeed Rajab 1,2 , Walter Swardfager 1,3 , Susan Marzolini 1,3 , Laura E. Middleton 3,4 , and Bradley J. MacIntosh 1,2
1
Heart & Stroke Foundation Canadian
Partnership for Stroke Recovery, Sunnybrook Research
Institute, University of Toronto, Toronto, ON, Canada,
2
Department
of Medical Biophysics, University of Toronto, Toronto,
ON, Canada,
3
Toronto
Rehabilitation Institute, University Health Network,
University of Toronto, Toronto, ON, Canada,
4
University
of Waterloo, Department of Kinesiology, Waterloo, ON,
Canada
We examined how exercise intensity affects cerebral
blood flow (CBF) following acute cycling in stroke.
Using arterial spin labeling, CBF estimates were made
before, 30 min after, and 50 min after exercise.
Participants exercised at low and moderate intensities
on separate days. CBF was changed after cycling,
independent of intensity, in areas within the right
basal ganglia and frontal lobe, and left temporal and
parietal lobes. The right parietal lobe, in particular,
was sensitive to intensity. In three areas, CBF
increased after moderate intensity cycling, relative to
light exercise. Parietal regions may provide a sensitive
biomarker for exercise-based stroke rehabilitation.
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