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Abstract #3527

A combined conventional ROI and Voxel based T2 relaxometry analysis in alcohol use disorders

Deepika Bagga 1 , Namita Singh 1 , Shilpi modi 1 , Prabhjot Kaur 1 , Subash Khushu 1 , Debajyoti Bhattacharya 2 , and Mohan lal Garg 3

1 INMAS, Delhi, Delhi, India, 2 Base Hospital, Delhi, India, 3 Panjab University, Chandigarh, India

MRI findings suggest structural, functional and metabolic alterations in chronic alcoholics. However, very few studies specifically sought to examine the alterations in associated hemodynamic or paramagnetic properties (as reflected by T2 relaxation times (T2-RT)) in this population. Thus, we carried out a T2 relaxometry study on alcohol dependents and control subjects .Alcohol dependent subjects showed increased T2 relaxation times in different brain regions suggestive of tissue disruption in these individuals which could, in part, be responsible for impaired cognitive abilities.

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