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Abstract #3358

Rapid, motion robust, and quiet quantitative magnetization transfer (qMT) imaging using a zero echo time (ZTE) acquisition

James H Holmes 1 , Alexey Samsonov 2 , Pouria Mossahebi 3 , Diego Hernando 2 , Aaron S Field 2,4 , and Kevin M Johnson 5

1 Global MR Applications and Workflow, GE Healthcare, Madison, WI, United States, 2 Radiology, University of Wisconsin-Madison, Madison, WI, United States, 3 Department of Medicine, University of Wisconsin-Madison, Madison, WI, United States, 4 Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States, 5 Medical Physics, University of Wisconsin-Madison, Madison, WI, United States

We demonstrate a method for rapid, motion robust, and quiet quantitative imaging using a time efficient zero echo time acquisition. The method relies on radial sampling to improve motion robustness and reduce scan time using an intermittent MT preparation pulse played every 64 imaging excitations rather than every TR. Quantitative parameters were calculated using a 3 parameter fit model to 2 SPGR imaging flip angle data sets, one MT weighted data set, and a B1 dataset. Results are shown for normal volunteers demonstrating motion robustness and potential for quantitative accuracy.

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