Abstract #3351
Combining CEST with CESL to differentiate slow exchanging pool from fast exchanging pool: mapping the concentration of Glutamate and Amides separately
Olivier E. Mougin 1 and Penny A Gowland 1
1
Sir Peter Mansfield Imaging Centre,
University of Nottingham, Nottingham, Nottinghamshire,
United Kingdom
Chemical Exchange Saturation Transfer (CEST) and
Chemical Exchange Spin Locking (CESL) have different
sensitivities to different exchanging pools. Here we
present a simple method to separate overlapping pools
such as APT and Glutamate based on a linear combination
of signals from different CEST and CESL sequences. The
method described here is directly applicable on clinical
scanner, and should prove useful in quantification of
fast exchanging proton pools
This abstract and the presentation materials are available to members only;
a login is required.
Join Here
