Abstract #3030
Potential effect of varying background B 0 gradients on diffusion measurements: an in silico study
Marco Palombo 1,2 , Chlo Najac 1,2 , and Julien Valette 1,2
1
CEA/DSV/I2BM/MIRCen, Fontenay-aux-Roses,
France, France,
2
CEA-CNRS
URA 2210, Fontenay-aux-Roses, France
Here we investigate the ability of double polarity
stimulated-echo (STE) and magic-ratio stimulated-echo (MAGSTE)
sequences in counteracting
susceptibility-induced-background-gradients (Gint).In
order to clarify if they compensate Gint effects on
DW-NMR signal, numerical simulations were performed.Our
results demonstrate that: 1) double polarity STE and
MAGSTE fully compensate only for Gint constant and equal
during preparation and read interval; 2) only MAGSTE
fully compensates for Gint varying in time in a
piecewise constant manner; 3) neither double polarity
STE nor MAGSTE can compensate for random and
uncorrelated Gint variations in space and time, which is
the most common condition in heterogeneous living
tissues.
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