Abstract #3029
Estimation of pore size distributions with diffusion MRI: feasibility for clinical scanners
Gaetan Duchene 1 , Frank Peeters 1 , and Thierry Duprez 1
1
Medical Imaging, Universit Catholique de
Louvain, Brussels, Brussels, Belgium
Pore size distribution (PSD) estimation has been
proposed using double pulsed field gradient sequences
with zero mixing time and infinite diffusion time under
the short gradient pulse approximation. Such an
idealization is not valid for clinical scanners. In this
work, we simulated data from MRI scanners (with finite
gradient duration). We investigated the resulting
systematic errors on the estimated PSDs as well as
random errors due to noise, and discuss the choice of
experimental parameters. We found that accurate
estimations are possible if the exact gradient waveform
is taken into account in the estimation procedure.
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