Abstract #2609
Comparison of High Resolution T 2 * Mapping and Quantitative Susceptibility Mapping to Investigate Myocardial Microstructure in the Ex Vivo Rodent Heart
Eva Peper 1 , Till Huelnhagen 1 , Andreas Pohlmann 1 , Min-Chi Ku 1 , and Thoralf Niendorf 1,2
1
Berlin Ultrahigh Field Facility (B.U.F.F.),
Max Delbrck Center for Molecular Medicine, Berlin,
Germany,
2
Experimental
and Clinical Research Center, a joint cooperation
between the Charit Medical Faculty and the Max Delbrck
Center, Berlin, Germany
This study investigates the tissue contrast for QSM of
ex
vivo
rodent
hearts at 9.4 T in comparison to T
2
*
mapping.
Results show that QSM can provide a higher contrast for
myocardial fiber structures than magnitude images and T
2
*
maps,
without using contrast agents. Susceptibility maps
showed good correlation with histological images from
literature. This observation provides encouragement that
QSM might be a useful tool for assessing myocardial
microstructure and could provide further insights into
myocardial fiber arrangement and myolaminar structure.
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