Abstract #2359
Application of pseudo-continuous arterial spin labeling for quantification of hepatic perfusion
Mike-Ely Cohen 1,2 , Isabelle Lajoie 2 , Kenneth Dyson 2 , Olivier Lucidarme 1,3 , Richard D. Hoge 2,4 , and Frdrique Frouin 1,5
1
Laboratoire d'imagerie biomedicale, Sorbonne
Universit Univ Paris 06, Inserm, CNRS, Paris, France,
2
Centre
de recherche de linstitut universitaire de griatrie de
Montral, Montral, Quebec, Canada,
3
Service
de Radiologie Polyvalente Diagnostique et Oncologique,
CHU Piti-Salptrire, AP-HP, Paris, France,
4
McConnell
Brain Imaging Centre, Montreal Neurological Institute -
McGill University, Quebec, Canada,
5
CEA/I2BM/SHFJ,
IMIV, Orsay, France
The purpose of this study was to optimize a
pseudo-Continuous Arterial Spin Labeling (pCASL)
approach to quantify hepatic perfusion among healthy
volunteers. Six volunteers were examined using a 3T
Siemens scanner, pCASL sequences with 4 to 20
measurements in a plane orthogonal to portal vein with a
post label delay (PLD) of 600 ms were acquired. For two
subjects, four additional PLD (from 1000 to 1600 ms)
were tested. Results show a more robust estimation when
using 20 measurements. Furthermore the five PLD values
provided hepatic perfusion weighted differently by the
hepatic artery and the portal vein blood flows.
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