Abstract #2329
Comparative Assessment of SAGE and GRE DSC Perfusion: Initial Assessment in a Stroke Cohort
Shalini A. Amukotuwa 1,2 , Fernando Calamante 2 , and Roland Bammer 1
1
Department of Radiology, Stanford
University, Stanford, CA, United States,
2
The
Florey Institute of Neuroscience and Mental Health,
University of Melbourne, Parkville, VIC, Australia
Combined spin- and gradient-echo (SAGE) dynamic
susceptibility contrast (DSC) perfusion-weighted imaging
(PWI) has considerable benefits over conventional
single-echo spin-echo (SE) or gradient-echo (GRE) DSC
PWI. However, mismatch criteria are based on GRE DSC
PWI. Our aim is to investigate the comparability of the
second gradient-echo of SAGE with GRE DSC PWI in
patients with suspected stroke. Our findings indicate
that, with matching scan parameters, the SAGE 2nd
gradient-echo yields comparable results to conventional
GRE DSC PWI; therefore SAGE data can be calibrated with
GRE DSC data, and postprocessing algorithms optimized
through previous clinical trials can be applied to SAGE.
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