Abstract #2112
Mapping epileptic networks using simultaneous EEG-MRI at ultra-high field
Frdric Grouiller 1 , Joo Jorge 2,3 , Francesca Pittau 4 , Pascal Martelli 1 , Wietske van der Zwaag 5 , Christoph M. Michel 6 , Serge Vullimoz 4 , Maria Isabel Vargas 1 , and Franois Lazeyras 1
1
Department of Radiology and Medical
Informatics, Geneva University Hospital, Geneva,
Switzerland,
2
Department
of Bioengineering, Institute for Systems and Robotics,
University of Lisbon, Lisbon, Portugal,
3
Laboratory
for Functional and Metabolic Imaging, Ecole
Polytechnique Fdrale de Lausanne, Lausanne,
Switzerland,
4
EEG
and Epilepsy Unit, Department of Neurology, Geneva
University Hospital, Geneva, Switzerland,
5
Biomedical
Imaging Research Center (CIBM), Ecole Polytechnique
Fdrale de Lausanne, Lausanne, Switzerland,
6
Functional
Brain Mapping Laboratory, University of Geneva, Geneva,
Switzerland
We report the feasibility to record simultaneous
EEG-fMRI at 7T in epileptic patients. We successfully
located epileptic networks using an optimized setup to
reduce environmental noise and appropriate artefacts
removal algorithms. The quality of intra-MR EEG allows
detecting interictal epileptiform discharges and
performing noise-sensitive topography-related analyses
to detect epilepsy-specific haemodynamic changes. These
results open new perspectives to better characterize
epileptic networks at higher field.
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