Abstract #2025
Inter-hemispheric Resting State Functional Connectivity in Anesthesia Induced Unconsciousness
Yuncong Ma 1 , Christina Hamilton 1 , Pablo D. Perez 1 , Zhifeng Liang 1 , and Nanyin Zhang 1
1
Department of Bioengineering, The
Pennsylvania State University, State College,
Pennsylvania, United States
The neural mechanism underlying anesthesia-induced
unconsciousness (AIU) remains elusive. In this study, we
aimed to investigate the system level circuit mechanism
of AIU by analyzing the inter-hemispheric resting-state
functional connectivity (RSFC) at the awake state and
five anesthetic depths. We used pairwise T Test to
reveal the connectivity changes from awake state to
various anesthesia states, and Pearson correlation to
compare the inter-hemispheric RSFC with behavioral data
across all AIU states.
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