Abstract #2019
Accelerated TE-Averaged Echo-Planar 3D Spectroscopic Imaging: Pilot Validation in Human Brain
Zohaib Iqbal 1 , Neil E. Wilson 1 , Brian L. Burns 1 , Margaret A. Keller 1 , and Michael Albert Thomas 1
1
University of California - Los Angeles, Los
Angeles, California, United States
This is a pilot demonstration of a novel technique,
called accelerated TE-averaged echo-planar Spectroscopic
Imaging (accelerated TEA-EPSI), which uses a combination
of an echo-planar readout and Compressed Sensing
reconstruction to achieve multi-slice TE-averaged
spectroscopic images in a clinically feasible time. The
data had non-uniform sampling applied along the ky,kz,t1
volume and were reconstructed using minimization of
total variation. Afterwards, the data were averaged over
the TE increments to obtain TE-averaged spectra. Brain
phantom data and in vivo brain spectra show good
reproducibility and high spectral quality, demonstrating
the potential usefulness of this technique for
investigating metabolic changes in different
pathologies.
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