Abstract #1945
Influence of different TE on reliability of brain metabolites quantification in high field 1H MRS
Veronika Rackayova 1 , Cristina Cudalbu 2 , Lijing Xin 1 , Nicolas Kunz 3 , Jana Starcukova 4 , Zenon Starcuk, Jr. 4 , and Rolf Gruetter 1,2
1
Laboratory of Functional and Metabolic
Imaging, Center for Biomedical Imaging, Ecole
Polytechnique Fdrale de Lausanne (EPFL), Lausanne,
Vaud, Switzerland,
2
Centre
d'Imagerie Biomedicale (CIBM), Ecole Polytechnique
Fdrale de Lausanne (EPFL), Lausanne, Vaud,
Switzerland,
3
Centre
d'Imagerie Biomedicale (CIBM-AIT), Ecole Polytechnique
Fdrale de Lausanne (EPFL), Lausanne, Vaud,
Switzerland,
4
Institute
of Scientific Instruments of the Academy of Sciences of
the Czech Republic, Brno, Czech Republic
With increasing magnetic field all metabolites have
tendency to shorten their apparent T2 relaxation time
and thus the use of ultra-short TE (<10ms) is
recommended. The aim was to test how TE affects the SNR,
the precision and the number of reliable quantifiable
metabolites. With increasing TE, we could observe
decreased number of quantifiable metabolites as well as
increase in mean CRLBs together with decreased SNR. As
expected, TE has an important effect on the reliability
of metabolites quantification. Ultra-short TE combined
with a reliable quantification software is a
preferential choice.
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