Abstract #1344
Task-induced deactivation in medial structures of the default mode network varied according to task types
Kayako Matsuo 1 , Katsuaki Suzuki 1 , Keisuke Wakusawa 2 , Kiyokazu Takebayashi 1 , Yasuo Takehara 3 , and Norio Mori 1
1
Department of Psychiatry, Hamamatsu
University School of Medicine, Hamamatsu, Shizuoka,
Japan,
2
Research
Center for Child Mental Development, Hamamatsu
University School of Medicine, Hamamatsu, Shizuoka,
Japan,
3
Department
of Radiology, Hamamatsu University School of Medicine,
Hamamatsu, Shizuoka, Japan
Task-induced deactivation (TID) is recently a focus of
fMRI research. It typically demonstrates maps of the
default mode network, showing relevance to cognitive
impairments. We investigated the changes of the TID in
the medial structures using visual, visuomotor and
counting tasks and the combination of the tasks. Demands
for cognitive processing affected the medial prefrontal
cortex, whereas task types modulated the posterior
cingulate cortex (PCC) and the precuneus. Hand action
reduced the TID of the area adjacent to the parieto-occipital
sulcus, which included the region frequently used as a
seed in functional connectivity analyses of
resting-state fMRI.
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