Abstract #1280
Novel probabilistic neonatal cortical brain atlas
Bonnie Alexander 1 , Andrea Murray 1 , Jian Chen 1,2 , Wai Yen Loh 1,3 , Claire Kelly 1 , Richard Beare 1 , Lillian Gabra Fam 1,4 , Peter Anderson 1,4 , Lex Doyle 1,5 , Alicia Spittle 1,5 , Jeanie Cheong 1,5 , Marc Seal 1,4 , and Deanne Thompson 1,3
1
Murdoch Childrens Research Institute,
Melbourne, Victoria, Australia,
2
Dept
of Medicine, Monash University, Melbourne, Australia,
3
Florey
Institute of Neuroscience and Mental Health, Melbourne,
Australia,
4
Dept
of Paediatrics, The University of Melbourne, Melbourne,
Australia,
5
Royal
Women's Hospital, Melbourne, Australia
This project addresses the need for a high quality
neonatal brain atlas attuned to accommodate tissue types
and morphological subtleties characteristic of this
developmental stage. T2 MRI scans of 3 healthy term-born
neonates were used. Cortical gray matter was segmented
using an in-house pipeline incorporating the unified
segmentation process implemented in SPM8. 33 cortical
areas per hemisphere were manually traced corresponding
to those in the Desikan-Killiany adult brain atlas. A
structural template was generated using symmetric
diffeomorphic transformation, and structure probability
maps were constructed. The atlas produced will be
incorporated into a freely accessible infant
segmentation and parcellation toolbox.
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