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Abstract #1191

Validation of adiabatic T 1 and T 2 mapping of articular cartilage at 3T

Victor Casula 1,2 , Joonas Autio 3 , Mikko J. Nissi 3,4 , Michaeli Shalom 4 , Silvia Mangia 4 , Edward Auerbach 4 , Jutta Ellermann 4 , Eveliina Lammentausta 3 , and Miika T. Nieminen 1,3

1 Department of Radiology, University of Oulu, Oulu, Oulu, Finland, 2 Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland, 3 Department of Diagnostic Radiology, Oulu University Hospital, Oulu, Finland, 4 Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, United States

Adiabatic T 1 lower case Greek rho and T 2 lower case Greek rho sequences were tested on a 3 T clinical system for mapping of articular cartilage. Phantom experiments with hyperbolic secant pulses (HS4) revealed excellent accuracy of the sequences and strong dependencies of R 1 lower case Greek rho and R 2 lower case Greek rho on agarose and chondroitin sulfate concentration, which are relevant for cartilage. The findings demonstrate that adiabatic T 1 lower case Greek rho and adiabatic T 2 lower case Greek rho techniques are promising tools for in vivo cartilage imaging at 3T.

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