Abstract #1188
Patients at risk for tendinopathy and chondropathy in patients with Diabetes mellitus Type I Identification by means of quantitative Sodium MR Imaging at ultra high field (7 Tesla) a feasibility study
Wolfgang Marik 1 , Stefan Nemec 2 , Stefan Zbyn 3 , Martin Zalaudek 3 , Bernhard Ludvik 4 , Manuela Karner 3 , and Siegfried Trattnig 3
1
Department of Biomedical Imaging and
Image-guided Therapy, Medical University of Vienna,
Vienna, Vienna, Austria,
2
Department
of Biomedical Imaging and Image-guided Therapy, Medical
University of Vienna, Vienna, Austria,
3
MR
Centre of Excellence, Department of Biomedical Imaging
and Image-guided Therapy, Medical University of Vienna,
Vienna, Austria,
4
Clinic for Internal Medicine
III, Department of Endocrinology and Metabolism, Medical
University of Vienna, Vienna, Austria
Purpose: Investigate biochemical alterations of tendons
and cartilage caused by DM Type 1 using quantitative in
vivo sodium MR imaging at 7 Tesla. Methods: Eight
patients with DM Type 1 and nine healthy volunteers were
examined on a 7 Tesla MR. All participants underwent
morphological and sodium image analysis. Region of
interest analysis was performed manually for the femoral
cartilage and patella tendon. For intra- and interreader
agreement two different readers solitary evaluated the
same image data sets. Results: Morphological imaging
revealed no difference between groups. Sodium MR imaging
revealed stasticaly significant altered NMSI values for
patients in cartilage an tendons (p=. 008; p= .025).
Conclusion: Statistically significant difference in NMSI
values was seen in patients compared with a healthy
control group.
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