Abstract #1142
Influence of Breast Cancer Receptor Status on Multi-parametric Magnetic Resonance Imaging for Predicting Treatment Response: Preliminary Results
Xia Li 1 , Vandana G Abramson 1 , Lori R. Arlinghaus 1 , Hakmook Kang 1 , Jason M Williams 1 , Richard G Abramson 1 , A. Bapsi Chakravarthy 1 , Praveen Pendyala 1 , and Thomas E Yankeelov 1
1
Vanderbilt University, Nashville, Tennessee,
United States
This study determines if classifying breast cancer
patients by subtype improves the ability of integrated
DCE-MRI and DW-MRI to predict eventual response after
the first cycle of NAC. The patients were divided into
three groups according to receptor status: 1)
ER-/PR-/HER2-, 2) HER2+, and 3) HR+/HER2-. These
preliminary results demonstrate that DCE- and DW-MRI may
be able to better predict treatment response for
patients with particular receptor status. This
observation should be confirmed in a large cohort in the
future.
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