Abstract #0924
Temporal-Variance Weighted P-space Multipole Frequency Mapping
Kyle S Decker 1,2 and Chunlei Liu 3,4
1
Center for In Vivo Microscopy, Duke
University, Durham, NC, United States,
2
Biomedical
Engineering, Duke University, Durham, NC, United States,
3
Brain
Imaging and Analysis Center, Duke University, Durham,
NC, United States,
4
Radiology,
Duke University, Durham, NC, United States
Through the use of improved processing methods, we are
able to use a single-shift p-space image reconstruction
to produce high fidelity multipole frequency maps using
multi-echo data. The temporal-variance of higher-order
multipole frequency distribution is dominant in the
white matter (WM), thus allowing the use of
temporal-variance to enhance multipole frequency maps of
WM in the p-space. This method suppresses artifacts in
isotropic regions including gray matter and allows
isolated characterization of sub-voxel WM anisotropy.
The resulting temporal-variance weighted p-space
multipole frequency maps provide a new contrast
mechanism with enhanced WM anisotropy and contrast.
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