Abstract #0892
Imaging oxygen extraction fraction in the visual cortex during functional activation using turbo QUIXOTIC
Jeffrey N Stout 1 , Elfar Adalsteinsson 1,2 , Bruce R Rosen 3 , and Divya S Bolar 3,4
1
Harvard-MIT Health Sciences and Technology,
Institute of Medical Engineering and Science, Cambridge,
Massachusetts, United States,
2
Department
of Electrical Engineering and Computer Science, MIT, MA,
United States,
3
Martinos
Center for Biomedical Imaging, MGH/Harvard Medical
School, MA, United States,
4
Department
of Radiology, Massachusetts General Hospital, Boston,
MA, United States
Using a turbo spin echo version of QUIXOTIC we measure
changes in oxygen extraction fraction (OEF) in the
visual cortex at baseline and during visual stimulation
in a fraction of the time required by the original
QUIXOTIC technique. The measured baseline and relative
change in oxygen extraction fraction (OEF) compares
favorably to literature values and suggests that with
further validation tQUIXOTIC MRI may be useful to
monitor regional OEF in the clinic.
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