Abstract #0848
Imaging of Dissolved-phase Hyperpolarized Xenon-129 in Human Kidneys
John P. Mugler, III 1 , G. Wilson Miller 1 , Craig H. Meyer 2 , Kun Qing 1 , Jaime F. Mata 1 , Steven Guan 2 , Kai Ruppert 1,3 , Iulian C. Ruset 4,5 , F. William Hersman 4,5 , and Talissa A. Altes 1
1
Radiology & Medical Imaging, University of
Virginia, Charlottesville, VA, United States,
2
Biomedical
Engineering, University of Virginia, Charlottesville,
VA, United States,
3
Cincinnati
Children's Hospital, Cincinnati, OH, United States,
4
Xemed,
LLC, Durham, NH, United States,
5
Physics,
University of New Hampshire, Durham, NH, United States
The purpose of this work was to determine if 129Xe can
be detected in human abdominal organs, such as the
kidneys. Dissolved-phase 129Xe imaging was performed at
1.5T in two healthy subjects. Dissolved-phase 129Xe was
seen in the kidneys of both subjects, and a linear
structure, consistent with the position of the
descending aorta, was seen passing between the kidneys
and bifurcating below the kidneys. These results may be
of interest for kidney perfusion imaging. In addition,
if multiple 129Xe resonances can be detected in the
kidneys, dissolved-phase 129Xe imaging may offer
additional interesting information on kidney function
and disease.
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