Abstract #0803
Adipokine secretions correlate with MRI measurements of adiposity
Kathryn Murray 1 , Caroline Hoad 1 , Jill Garratt 2 , Carolyn Costigan 1 , Arvind Batra 3 , Britta Siegmund 3 , Yirga Falcone 2 , Jan Smith 2 , Eleanor Cox 1 , Jan Paul 1 , David Humes 2 , Susan Francis 1 , Luca Marciani 2 , Robin Spiller 2 , and Penny Gowland 1
1
Sir Peter Mansfield Imaging Centre, Physics
and Astronomy, University of Nottingham, Nottingham,
United Kingdom,
2
Nottingham
Digestive Diseases Biomedical Research Centre,
Nottingham University Hospitals, Nottingham, United
Kingdom,
3
Gastroenterology,
Rheumatology, Infectious Diseases, Charit
Universittsmedizin, Berlin, Germany
This study highlights the relationship between adipose
deposition, adipokine secretion and intestinal
inflammation using obese and non-obese patients with
diverticular disease. DIXON imaging was used to
determine VAT, SAT and TAT amounts and these volumes
were compared to concentrations of adiponectin, leptin
and calprotectin. These novel insights will help improve
our understanding of the relationship between visceral
fat, obesity and inflammation.
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