Abstract #0795
Assessing relationship between intracranial vascular compliance and aortic pulse wave velocity using MRI
Lirong Yan 1 , Collin Liu 2 , Robert Smith 1 , Mayank Jog 1 , Kate Krasileva 1 , Cheng Li 3 , Michael Langham 3 , and Danny JJ Wang 1
1
Neurology, University of California Los
Angeles, Los Angeles, CA, United States,
2
University
of Southern California, CA, United States,
3
University
of Pennsylvania, Philadelphia, PA, United States
The purpose of this study was to investigate the
relationship between intracranial vascular compliance
and aortic pulse wave velocity (PWV) in a cohort of
subjects with mixed vascular risks. We found there was
significant negative correlation between intracranial VC
and aortic PWV. Subjects with high vascular risks showed
reduced intracranial VC and elevated aortic PWV compared
to subjects with low vascular risks. These findings
suggest that changes in vascular compliance typically
extend from aorta to intracranial vessels.
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