Abstract #0724
Age-related changes of the human brain: Insights from double-wave vector imaging
Marco Lawrenz 1,2 , Stefanie Brassen 1,2 , and Jrgen Finsterbusch 1,2
1
Department of Systems Neuroscience,
University Medical Center Hamburg-Eppendorf, Hamburg,
Hamburg, Germany,
2
Neuroimage
Nord, University Medical Centers Hamburg-Kiel-Lbeck,
Hamburg-Kiel-Lbeck, Hamburg-Kiel-Lbeck, Germany
Double-wave-vector diffusion-weighting experiments with
two weighting periods applied successively offer access
to microscopic tissue. Rotationally invariant measures
of the microscopic diffusion anisotropy such as the MA
index may yield additional information complementary to
DTI. Recent studies showed that MA can be determined in
the living human brain, and normal values and their
variation in a group of young healthy volunteers have
been reported. In this study, DWV and DTI measurements
were performed in a group of old, healthy volunteers in
order to detect age-related changes of the FA and MA.
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