Abstract #0538
Measuring myocardial blood flow using modified look locker inversion (MOLLI) recovery arterial spin labelling (ASL)
Charlotte E Buchanan 1 , Eleanor F Cox 1 , Claire Grant 2 , Nick M Selby 2 , Chris W McIntyre 3 , Maarten W Taal 2 , and Susan T Francis 1
1
SPMIC, University of Nottingham, Nottingham,
Nottinghamshire, United Kingdom,
2
Division
of Medical Sciences and Graduate Entry Medicine, Royal
Derby Hospital, Nottingham, United Kingdom,
3
Schulich
School of Medicine and Dentistry, University of Western
Ontario, London, Ontario, Canada
A modified look locker inversion (MOLLI) recovery
arterial spin labelling (ASL) technique is used to
measure myocardial blood flow (MBF) in humans. Cardiac
triggering was used with a Trigger-delay (TD) prior to
the label module to allow data to be collected at a
range of post-label delay times. 8 TD values were
collected (0 - 350 ms), with 3 readout pulses per
Look-Locker set. MBF was 1.25 0.45 and 1.34 0.42
ml/g/min in healthy controls and chronic kidney disease
patients. On exercise, the mean increase in MBF was 85
24 % for patients.
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