Abstract #0353
A machine learning based approach to fiber tractography
Peter F. Neher 1 , Michael Gtz 1 , Tobias Norajitra 1 , Christian Weber 1 , and Klaus H. Maier-Hein 1
1
Medical Image Computing Group, German Cancer
Research Center (DKFZ), Heidelberg, Germany
Current tractography pipelines incorporate several
modelling assumptions about the nature of the
diffusion-weighted signal. We present a purely
data-driven and thus fundamentally new approach that
tracks fiber pathways by directly processing raw signal
intensities. The presented method is based on a random
forest classification and voting process that guides
each step of the streamline progression. We evaluated
our approach quantitatively and qualitatively using
phantom and in vivo data. The presented machine learning
based approach to fiber tractography is the first of its
kind and our experiments showed promising performance
compared to 12 established state of the art tractography
pipelines.
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