Abstract #0295
Cerebral venous thrombosis: direct thrombus imaging with sub-millimeter isotropic resolution dark-blood MRI
Zhaoyang Fan 1 , Qi Yang 1,2 , Xiaofeng Qu 1,3 , Yibin Xie 1,4 , Guoxi Xie 5 , Tianyi Qian 6 , Xiaoming Bi 7 , Yutaka Natsuaki 7 , and Debiao Li 1
1
Biomedical Imaging Research Institute,
Cedars-Sinai Medical Center, Los Angeles, California,
United States,
2
Radiology,
Xuanwu Hospital, Beijing, China,
3
Radiology,
The Second Hospital OF Dalian Medical University,
Dalian, China,
4
Bioengineering,
University of California, Los Angeles, California,
United States,
5
Shenzhen
Institutes of Advanced Technology, Chinese Academy of
Sciences, Guangdong, China,
6
MR
Collaboration NE Asia, Siemens Healthcare, Beijing,
China,
7
MR
R&D, Siemens Healthcare, Los Angeles, California, United
States
Cerebral venous thrombosis (CVT) is a disorder
potentially leading to devastating disability and even
death if not timely diagnosed and treated. Diagnosis is
challenging with the current clinical imaging modalities
due to various image artifacts and the variation in
venous anatomy. We hypothesized that
high-spatial-resolution dark-blood MRI, commonly used
for artery wall imaging, may be a useful tool. In this
work, a T1-weighted DANTE-prepared 3D TSE technique was
developed to provide direct visualization of thrombus
and surrounding anatomic structures in cerebral venous
system. Our preliminary clinical study demonstrated that
the technique may outweigh TOF MRV in diagnosing CVT.
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