Abstract #0093
Slice Blipped EPI Trajectory for Compressed Sensing Acquisition of 3D Time Resolved Imaging of Hyperpolarized [1- 13 C]Pyruvate and [1- 13 C]Lactate
Benjamin J. Geraghty 1,2 , Justin Y.C. Lau 1,2 , Albert P. Chen 3 , William Dominguez-Viqueira 1 , and Charles H. Cunningham 1,2
1
Imaging Research, Sunnybrook Health Sciences
Centre, Toronto, Ontario, Canada,
2
Dept.
of Medical Biophysics, University of Toronto, Toronto,
Ontario, Canada,
3
GE
Healthcare, Toronto, Ontario, Canada
Spectral-spatial excitation can be used for rapid time
resolved 3D acquisitions; however, maintaining adequate
spatial and temporal resolution is limited by the
required field-of-view coverage. Here, we demonstrate a
slice blipped EPI compressed sensing acquisition
strategy for accelerated 3D time resolved imaging of
[1-13C]pyruvate and lactate across a large
field-of-view. Image reconstructions of both
retrospectively and prospectively 2X undersampled in
vivo data is presented. Close agreement is shown between
fully and undersampled lactate to pyruvate area under
curve ratio.
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